Sir Alex Ferguson suffered the ignominy of watching his Manchester United side lose to basement club Blackburn on his 70th birthday.
Yakubu gave Rovers the lead from the spot after Dimitar Berbatov had pulled down defender Chris Samba.
The Nigerian made it 2-0 when he made the most of slack defending to thrash in, before Berbatov brought United back into the match with a header and shot.
But Grant Hanley spoilt the day for Ferguson when he nodded in the winner.
Hanley exemplified the spirit of Steve Kean's Blackburn of late. A draw at Anfield last week has now been followed up with arguably the greatest victory of his managerial career.
The win, which bookies had at 28-1 prior to the match, moves Rovers off the bottom, and only three points shy of 17th.
It should give Kean some respite from the supporters, who have been calling for his resignation.
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